منابع مشابه
Update on rivastigmine.
BACKGROUND Rivastigmine is a carbamate drug designed to inhibit both acetylcholinesterase and butyrylcholinesterase by reversibly covalently bonding to these enzymes. Butyrylcholinesterase in-creases as Alzheimer disease progresses, so its inhibition may become more important as the disease worsens. Metabolism of rivastigmine occurs at the synapse rather than at the liver and previous studies h...
متن کاملCase Report Rivastigmine in Wernicke-korsakoff’s Syndrome: Five Patients with Rivastigmine Showed No More Improvement than Five Patients without Rivastigmine
Aims: To evaluate whether rivastigmine, an achetylcholinesterase inhibitor (AChEl), may be effective in restoring memory in Wernicke-Korsakoff’s syndrome (WKS). Methods: Five patients treated with rivastigmine for a period of 6 months were compared with five matched control patients, who received 6 months’ conventional treatment, but without rivastigmine. Memory tests were administered at basel...
متن کاملRivastigmine in Wernicke-Korsakoff's syndrome: five patients with rivastigmine showed no more improvement than five patients without rivastigmine.
AIMS To evaluate whether rivastigmine, an achetylcholinesterase inhibitor (AChEl), may be effective in restoring memory in Wernicke-Korsakoff's syndrome (WKS). METHODS Five patients treated with rivastigmine for a period of 6 months were compared with five matched control patients, who received 6 months' conventional treatment, but without rivastigmine. Memory tests were administered at basel...
متن کاملIdentification of responders to rivastigmine: a prospective cohort study.
BACKGROUND Although the overall effects of cholinesterase inhibitors (CEIs) are limited, there could be a subpopulation of patients who experience unequivocal benefit. This study aimed to describe a clinical profile based on a combination of specific neuropsychological test scores and clinical symptoms associated with a favourable response to rivastigmine. METHODS A prospective cohort study w...
متن کاملAn Atypical Cutaneous Reaction to Rivastigmine Transdermal Patch
Rivastigmine is a cholinesterase inhibitor which improves cognitive function and is currently being used in patients with mild to moderate Parkinson's and Alzheimer's dementia. This drug can be given orally or topically, as transdermal patch. The latter form is currently used for most excellent compliance and few side effects. The most common cutaneous side effects are irritative dermatitis. We...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 2019
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.2137-18